The Apostle Paul's first missionary journey / Acts Bible Study Chapter 13 (TV Audio #488)

'While they were worshiping the Lord and fasting, the Holy Spirit said, “Set apart for me Barnabas and Saul for the work to which I have called them.” So after they had fasted and prayed, they placed their hands on them and sent them off.' (Acts 13.2-3, NIV.) Acts 13 details the start of Paul's first missionary journey:

Commissioning of Paul and Barnabas: The chapter begins with the church in Antioch commissioning Paul and Barnabas for missionary work. The Holy Spirit directs this decision.
Preaching in Cyprus: Paul and Barnabas travel to Cyprus, where they preach the word of God in synagogues. They encounter Bar-Jesus, a false prophet, whom Paul rebukes for trying to turn the proconsul away from the faith.
Preaching in Pisidian Antioch: They journey to Pisidian Antioch and preach in the synagogue there. Paul gives a powerful sermon recounting Israel's history and how Jesus fulfills God's promises. Many Jews and Gentiles believe, but some Jews oppose them, leading to their expulsion from the region.
Turning to the Gentiles: Paul and Barnabas turn their focus to the Gentiles, spreading the Gospel throughout the region. The message spreads rapidly.
Opposition and Perseverance: Despite facing opposition and persecution, Paul and Barnabas continue to preach boldly, relying on God's strength.

The chapter concludes with Paul and Barnabas departing from Pisidian Antioch, shaking the dust off their feet as a symbolic gesture against those who reject the Gospel, and moving on to preach in Iconium.